A combination of metformin and epigallocatechin gallate potentiates glioma chemotherapy in vivo
Glioma is the most devastating high-grade tumor of the central nervous system, with dismal prognosis.Existing treatment modality does not provide substantial benefit to patients and demands novel strategies.One of the first-line treatments for glioma, temozolomide, provides marginal benefit to glioma patients.Repurposing of existing non-cancer drug